Dr. Joshua Griffin, MD

Josh Griffin did not grow up dreaming of becoming a doctor. He grew up in Maben, Mississippi, a town small enough that ambition had to be self-generated. What he had was a mind that liked hard things and a stubbornness that wouldn’t let him quit once he started something. Medicine didn’t call to him in childhood — he found it the way most people find their true purpose: by following the challenge until the challenge became a calling.

Halfway through his sophomore year in college, while working through the prerequisites for physical therapy school, Griffin realized something. He was making excellent grades. These were the same prerequisites for medical school. And so, with the logic of a man who was never going to do anything halfway, he thought: what the hell, why not. He applied to the University of Mississippi Medical Center. He got in on his first attempt. He never looked back.

Medical school, Griffin will tell you, drew him in through sheer intellectual force. He had spent a year in college dissecting biochemistry. Medical school covered the same material in nine weeks. The depth, the pace, the weight of what medicine actually was — it suited him completely. As he moved through his clinical rotations, urology found him. He was hooked. No turning back.

He completed his urology residency at the University of Mississippi Medical Center in Jackson, finishing in 2011. Driven by a desire to push further, he pursued a fellowship in Urologic Oncology at the University of Kansas Medical Center — two years working alongside an exceptional group of robotic surgeons, building clinical databases and contributing to research in prostate and bladder cancer. He earned his Diplomate certification from the American Board of Urology in 2014 and returned to Mississippi to build a career.

For the first several years, Dr. Griffin practiced traditional urology in Columbus, Mississippi. He was thorough, technically skilled, and genuinely interested in the patients in front of him. He had a habit — one that would eventually change everything — of asking at the end of every encounter: “Is there anything else I can do for you today?” That question, he says, can open up a Pandora’s box. Patients started answering honestly. Joint pain. Fatigue. Sexual issues. Sleep. “I just don’t have any desire to be intimate with my spouse anymore.” “I sleep eight hours but by 3 PM I have no energy to live a healthier life.” Griffin could have said: not my specialty. He couldn’t.

The common thread he kept finding in his research was the failure — his own included — to acknowledge the importance of hormone balance. His wife, Dr. Meredith Griffin, an OB-GYN who had incorporated pellet therapy into her own practice, was seeing remarkable results in her female patients. She had noticed significant improvements in her own energy, sleep, and wellbeing. The evidence was personal before it was clinical. After relocating to Oxford in 2018 and joining Oxford Urology Associates, Griffin had the resources — staff, rooms, time — to act. In September 2019, he added comprehensive hormone pellet therapy to his practice. Within a short time it had grown into a completely separate operation with two locations.

What he found on the other side of that door was not a side business. It was a new lens on medicine entirely. As a urologist, Dr. Griffin had long understood the connections between sexual health, cardiovascular disease, and metabolic function. Erectile dysfunction is a potential early marker for cardiovascular risk. Testosterone deficiency is a flag for a range of metabolic conditions. In his own clinical experience, some of the most aggressive prostate cancers he has treated have been in men with low or low-normal testosterone — an observation supported by a growing body of literature challenging the outdated belief that testosterone feeds prostate cancer. The deeper he went, the more clearly he saw how much the conventional medical system had undersold this territory.

His philosophy on treatment is patient-specific by design. The ReviveMD dosing approach accounts for weight, age, activity level, prior hormone history, and patient goals — not a formula, but a conversation that begins with a number and is refined through structured follow-up, lab work, and a post-pellet symptom survey. He does not believe in treating to a lab range. He believes in treating to the person. “Once I started thinking in terms of optimal rather than ‘normal range,’” he says, “the shift happened, and there was no turning back.”

The stories that came out of the clinic confirmed it. A burned-out executive who came in having lost all desire for life left saying Griffin had taken him “from the bottom floor to the penthouse.” A young father on antidepressants and sleep medications who, after optimization, was eventually able to come off both — his mood restored, his function returned, his will to live back. These are not outliers. They are the reason Dr. Griffin does this work.

Today, Dr. Griffin holds hospital affiliations at Baptist Memorial Hospital North Mississippi in Oxford and North Mississippi Medical Center in Tupelo. He is a member of the American Urological Association, the American Academy of Anti-Aging Medicine, and the International Peptide Society. He was the first urologist in Mississippi to offer Aquablation, a minimally invasive treatment for prostate enlargement. He has personally performed or supervised well over a thousand pellet therapy procedures and has trained five nurse practitioners who work alongside him in the Revive clinics.

Outside of medicine, Griffin runs, rides his Peloton, lifts weights, and practices yoga when the schedule allows. He writes in journals with fountain pens, collects and listens to vinyl records, plays guitar and piano, and has recently picked up the bass. He lives in Oxford, Mississippi with his wife Dr. Meredith Griffin and their two sons, Anders and Harris.